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Image Search Results
Journal: Frontiers in Medicine
Article Title: Deciphering CHFR Role in Pancreatic Ductal Adenocarcinoma
doi: 10.3389/fmed.2021.720128
Figure Lengend Snippet: CHFR methylation analysis of human samples, borderline (A–F) and resectable cohort (G–L) . Methylation-Specific PCR (left) and Pyrosequencing Assay (right). T (tumoral tissue) and A (Adjacent tissue). *Statistically significant differences ( p < 0.05). Columns represents mean and error bars correspond to standard deviations.
Article Snippet: It was in the latter cohort where we were able to establish the utility of this
Techniques: Methylation, Pyrosequencing Assay
Journal: Frontiers in Medicine
Article Title: Deciphering CHFR Role in Pancreatic Ductal Adenocarcinoma
doi: 10.3389/fmed.2021.720128
Figure Lengend Snippet: Correlation of CHFR methylation with clinical outcomes in resectable patients. Kaplan-meier curve representing OS for resectable cohort and dichotomized by CpG-2 median methylation percentage.
Article Snippet: It was in the latter cohort where we were able to establish the utility of this
Techniques: Methylation
Journal: Frontiers in Allergy
Article Title: Mast Cell Desensitization in Allergen Immunotherapy
doi: 10.3389/falgy.2022.898494
Figure Lengend Snippet: Potential biomarkers in AIT.
Article Snippet:
Techniques: In Vivo, Activity Assay, Activation Assay, Functional Assay, DNA Methylation Assay, Expressing
Journal: Frontiers in Cell and Developmental Biology
Article Title: (Multi-) omics studies of ILC2s in inflammation and metabolic diseases
doi: 10.3389/fcell.2024.1473616
Figure Lengend Snippet: ILC2 metabolism in healthy and diseased state (A) In healthy homeostatic state, ILC2s use glycolysis and FAO to fuel OXPHOS for the production of IL-5, IL-13 cytokines to maintain their survival. (B) Upon helminth infection in the lung, IL-33 is released which in turn activates ILC2s, leading to FAO and Arg1 activity for IL-13 production in order to enhance the anti-inflammatory and tissue-repair functions of ILC2s. (C) In metabolic disorders, impaired metabolism due to high glucose and free fatty acids (FFA), ILC2 metabolism is disrupted, partly leading to increased glycolysis to manage the excess of glucose Abbreviations: Arginase-1 (Arg1), Fatty acid oxidation (FAO), Free fatty acids (FFA), Innate lymphoid cells type 2 (ILC2s), Interleukin (IL), oxidative phosphorylation (OXPHOS). Made with biorender.com . The “?” indicates that there is a yet unknown mechanism.
Article Snippet:
Techniques: Infection, Activity Assay, Phospho-proteomics
Journal: Frontiers in Cell and Developmental Biology
Article Title: (Multi-) omics studies of ILC2s in inflammation and metabolic diseases
doi: 10.3389/fcell.2024.1473616
Figure Lengend Snippet: Overview of ILC2 focused omics approaches.
Article Snippet:
Techniques: DNA Methylation Assay, Modification, Biomarker Discovery, Quantitative Proteomics, Expressing, Protein-Protein interactions